EP-2007: Radiomics based method to predict overall survival of inoperable NSCLC patients

Beyond survival: economic analyses of chemotherapy in advanced, inoperable NSCLC.

Research shows that chemotherapy for inoperable non-small-cell lung cancer (NSCLC) improves survival. The economic implications of this treatment choice may be substantial. This paper reviews studies examining the cost-effectiveness of chemotherapy in this setting. MEDLINE, PDQ, Cancerlit, EMBASE, and the Nursing & Allied Health databases were searched using the terms cost, cost-effectiveness, ...

Prognostic Model to Predict Overall Survival for Patients with Middle Ear Cancer: A Population-based analysis

Circulating DNA: Diagnostic Tool and Predictive Marker for Overall Survival of NSCLC Patients

PURPOSE The purpose of our study was to determine whether the amounts of circulating DNA (cDNA) could discriminate between NSCLC patients and healthy individuals and assess its value as a prognostic marker of this disease. METHODS We conducted a study of 309 individuals and the cDNA levels were assessed through real-time PCR methodology. RESULTS We found increased cDNA levels in NSCLC patie...

Progression-Free and Overall Survival in ALK-Positive NSCLC Patients Treated with Sequential Crizotinib and Ceritinib.

PURPOSE Anaplastic lymphoma kinase (ALK) rearrangements are important therapeutic targets in non-small cell lung cancer (NSCLC) that confer sensitivity to the ALK inhibitors crizotinib and ceritinib. To determine the outcome of sequential treatment with crizotinb and ceritinib, we retrospectively evaluated a cohort of ALK-positive patients treated with both agents. EXPERIMENTAL DESIGN We iden...

A longitudinal analysis with CA-125 to predict overall survival in patients with ovarian cancer

OBJECTIVE The objective of this study was to explore the association of longitudinal CA-125 measurements with overall survival (OS) time by developing a flexible model for patient-specific CA-125 profiles, and to provide a simple and reliable prediction of OS. METHODS A retrospective study was performed on 275 patients with ovarian cancer who underwent at least one cycle of primary chemothera...